› 1yxe

Solution NMR

Structure and inter-domain interactions of domain II from the blood stage malarial protein, apical membrane antigen 1

Released:
DOI: 10.2210/pdb1yxe/pdb
PDB entry 1yxe coloured by chain, ensemble of 20 models, front view.
PDB entry 1yxe coloured by chain, ensemble of 20 models, side view.
PDB entry 1yxe coloured by chain, ensemble of 20 models, top view.
Source organism: Plasmodium falciparum 3D7
Primary publication:
Structure and inter-domain interactions of domain II from the blood-stage malarial protein, apical membrane antigen 1.
Feng ZP, Keizer DW, Stevenson RA, Yao S, Babon JJ, Murphy VJ, Anders RF, Norton RS
J Mol Biol 350 641-56 (2005)
PMID: 15964019

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149680 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apical membrane antigen 1 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 15.98 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22621 (Residues: 309-436; Coverage: 21%)
Gene names: AMA-1, PF83
Structure domains: Hepatocyte Growth Factor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Apical membrane antigen 1: a malaria vaccine candidate in review.
Remarque et al. (2008)
3 more

1 mention without citation

Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter.
Darling et al. (2018)