› 1yz6

X-ray diffraction
3.37Å resolution

Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi

Released:
DOI: 10.2210/pdb1yz6/pdb
PDB entry 1yz6 coloured by chain, front view.
PDB entry 1yz6 coloured by chain, side view.
PDB entry 1yz6 coloured by chain, top view.
Source organism: Pyrococcus abyssi
Primary publication:
Structure-function relationships of the intact aIF2alpha subunit from the archaeon Pyrococcus abyssi.
Yatime L, Schmitt E, Blanquet S, Mechulam Y
Biochemistry 44 8749-56 (2005)
PMID: 15952781

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194153 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Translation initiation factor 2 subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 31.84 KDa
Source organism: Pyrococcus abyssi
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9V0E4 (Residues: 2-275; Coverage: 100%)
Gene names: PAB0568, PYRAB08460, aif2A, eif2a
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P3121
Unit cell:
a: 104.329Å b: 104.329Å c: 129.367Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.272 0.25 0.29
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs).
Valásek LS. (2012)
4 more

4 mentions without citation

The roles of S1 RNA-binding domains in Rrp5's interactions with pre-rRNA.
Young et al. (2011)
3 more