› 1z06

X-ray diffraction
1.81Å resolution

GppNHp-Bound Rab33 GTPase

Released:
DOI: 10.2210/pdb1z06/pdb
PDB entry 1z06 coloured by chain, front view.
PDB entry 1z06 coloured by chain, side view.
PDB entry 1z06 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Eathiraj S, Pan X, Ritacco C, Lambright DG
Nature 436 415-9 (2005)
PMID: 16034420

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128721 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-33B Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 21.68 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O35963 (Residues: 30-202; Coverage: 76%)
Gene name: Rab33b
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand GNP 1 x GNP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P32
Unit cell:
a: 56.194Å b: 56.194Å c: 55.039Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.189 0.218
Expression system: Escherichia coli

Quick links

Citations

29 review citations

Rab GTPases as coordinators of vesicle traffic.
Stenmark H. (2009)
28 more

10 mentions without citation

Structural mechanisms for regulation of membrane traffic by rab GTPases.
Lee et al. (2009)
9 more