We've built a new version of this page with an interactive 3D viewer. Try it out in beta and help us improve:

› 1z1a

X-ray diffraction
2.5Å resolution

S. cerevisiae Sir1 ORC-interaction domain

Released:
DOI: 10.2210/pdb1z1a/pdb
Model geometry
Fit model/data
PDB entry 1z1a coloured by chain, front view.
PDB entry 1z1a coloured by chain, side view.
PDB entry 1z1a coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing.
Hou Z, Bernstein DA, Fox CA, Keck JL
Proc Natl Acad Sci U S A 102 8489-94 (2005)
PMID: 15932939

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149360 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein SIR1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 142 amino acids
Theoretical weight: 16.85 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P21691 (Residues: 449-587; Coverage: 21%)
Gene names: SIR1, YKR101W
Sequence domains: Sir1, ORC-binding domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 14-ID-B
Spacegroup: P3221
Unit cell:
a: 60.928Å b: 60.928Å c: 159.257Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.241 0.238 0.274
Expression system: Escherichia coli BL21

Quick links

Citations

12 review citations

High-resolution protein-protein docking.
Gray JJ. (2006)
11 more

5 mentions without citation

Protein-protein docking benchmark version 3.0.
Hwang et al. (2008)
4 more