› 1z3i

X-ray diffraction
3Å resolution

Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54

Released:
DOI: 10.2210/pdb1z3i/pdb
PDB entry 1z3i coloured by chain, front view.
PDB entry 1z3i coloured by chain, side view.
PDB entry 1z3i coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54.
Thomä NH, Czyzewski BK, Alexeev AA, Mazin AV, Kowalczykowski SC, Pavletich NP
Nat Struct Mol Biol 12 350-6 (2005)
PMID: 15806108

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-123337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair and recombination protein RAD54-like Chain: X
Molecule details ›
Chain: X
Length: 644 amino acids
Theoretical weight: 73.03 KDa
Source organism: Danio rerio
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: F1Q8K0 (Residues: 92-735; Coverage: 87%)
Gene name: rad54l
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand SO4 9 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: R32
Unit cell:
a: 205.046Å b: 205.046Å c: 189.958Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.234
Expression system: Spodoptera frugiperda

Quick links

Citations

30 review citations

Structure and mechanism of helicases and nucleic acid translocases.
Singleton et al. (2007)
29 more

26 mentions without citation

Rad54: the Swiss Army knife of homologous recombination?
Heyer et al. (2006)
25 more