› 1z6g

X-ray diffraction
2.18Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + GMP = ADP + GDP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184646 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
guanylate kinase Chain: A
Molecule details ›
Chain: A
Length: 218 amino acids
Theoretical weight: 25.58 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8I2M1 (Residues: 1-199; Coverage: 100%)
Gene name: PF3D7_0928900
Sequence domains: Guanylate kinase
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand SO4 5 x SO4
Ligand EPE 1 x EPE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 41.42Å b: 47.24Å c: 118.245Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.219 0.269
Expression system: Escherichia coli

Quick links

Citations

33 review citations

Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins.
Hall et al. (2011)
32 more

2 mentions without citation

Native Mass Spectrometry in Fragment-Based Drug Discovery.
Pedro et al. (2016)
1 more