› 1z77

X-ray diffraction
2Å resolution

Crystal structure of transcriptional regulator protein from Thermotoga maritima.

Released:
DOI: 10.2210/pdb1z77/pdb
PDB entry 1z77 coloured by chain, front view.
PDB entry 1z77 coloured by chain, side view.
PDB entry 1z77 coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment.
Koclega KD, Chruszcz M, Zimmerman MD, Cymborowski M, Evdokimova E, Minor W
J Struct Biol 159 424-32 (2007)
PMID: 17588774

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194690 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 200 amino acids
Theoretical weight: 24.21 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X0C0 (Residues: 1-200; Coverage: 100%)
Gene name: TM_1030
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EDO 2 x EDO
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID, APS BEAMLINE 19-BM
Spacegroup: P21212
Unit cell:
a: 56.043Å b: 65.684Å c: 55.694Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.229 0.267
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Determination of protein structures--a series of fortunate events.
Chruszcz et al. (2008)
1 more

5 mentions without citation

Crystal structure of the Vibrio cholerae quorum-sensing regulatory protein HapR.
De Silva et al. (2007)
4 more