1z8l

X-ray diffraction
3.5Å resolution

Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase.
Proc Natl Acad Sci U S A 102 5981-6 (2005)
PMID: 15837926

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-170042 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Glutamate carboxypeptidase 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 695 amino acids
Theoretical weight: 78.34 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q04609 (Residues: 56-750; Coverage: 93%)
Gene names: FOLH, FOLH1, GIG27, NAALAD1, PSM, PSMA
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, NDG
Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 74.865Å b: 157.765Å c: 133.839Å
α: 90° β: 93.24° γ: 90°
R-values:
R R work R free
0.252 0.252 0.284
Expression system: Not provided