› 1z9x

X-ray diffraction
3.93Å resolution

Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 3 monomers in the asymmetric unit

Released:
DOI: 10.2210/pdb1z9x/pdb
PDB entry 1z9x coloured by chain, front view.
PDB entry 1z9x coloured by chain, side view.
PDB entry 1z9x coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kursula P, Lehmann F, Shani G, Kimchi A, Wilmanns M

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193791 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death-associated protein kinase 2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 321 amino acids
Theoretical weight: 37.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UIK4 (Residues: 11-330; Coverage: 87%)
Gene name: DAPK2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: C2
Unit cell:
a: 126.4Å b: 62.99Å c: 150.97Å
α: 90° β: 110.98° γ: 90°
R-values:
R R work R free
0.33 0.328 0.351
Expression system: Escherichia coli

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