› 1zei

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin B chain Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 53 amino acids
Theoretical weight: 5.99 KDa
Source organism: Sus scrofa
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P01315 (Residues: 25-54, 88-108; Coverage: 61%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like

Ligands and Environments

3 bound ligands:
Ligand CRS 8 x CRS
Ligand ZN 2 x ZN
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: P21
Unit cell:
a: 53.952Å b: 64.772Å c: 48.914Å
α: 90° β: 109.81° γ: 90°
R-values:
R R work R free
0.176 0.176 0.232
Expression system: Saccharomyces cerevisiae

Quick links

Citations

19 review citations

Frustration in biomolecules.
Ferreiro et al. (2014)
18 more