› 1zfl

Solution NMR

Solution structure of III-A, the major intermediate in the oxidative folding of leech carboxypeptidase inhibitor

Released:
DOI: 10.2210/pdb1zfl/pdb
PDB entry 1zfl coloured by chain, ensemble of 20 models, front view.
PDB entry 1zfl coloured by chain, ensemble of 20 models, side view.
PDB entry 1zfl coloured by chain, ensemble of 20 models, top view.
Source organism: Hirudo medicinalis
Primary publication:
NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor.
Arolas JL, D'Silva L, Popowicz GM, Aviles FX, Holak TA, Ventura S
Structure 13 1193-202 (2005)
PMID: 16084391

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160531 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallocarboxypeptidase inhibitor Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.4 KDa
Source organism: Hirudo medicinalis
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P81511 (Residues: 16-81; Coverage: 100%)
Structure domains: Carboxypeptidase inhibitor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

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Citations

3 review citations

Folding of small disulfide-rich proteins: clarifying the puzzle.
Arolas et al. (2006)
2 more