› 1zob

X-ray diffraction
2.75Å resolution

Crystal structure of dialkylglycine decarboxylases bound with calcium ion

Released:
DOI: 10.2210/pdb1zob/pdb
PDB entry 1zob coloured by chain, front view.
PDB entry 1zob coloured by chain, side view.
PDB entry 1zob coloured by chain, top view.
Source organism: Burkholderia cepacia
Entry authors: Liu W, Toney MD

Function and Biology Details

Reaction catalysed: 
2,2-dialkylglycine + pyruvate = dialkyl ketone + CO(2) + L-alanine
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-147845 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2,2-dialkylglycine decarboxylase Chain: A
Molecule details ›
Chain: A
Length: 433 amino acids
Theoretical weight: 46.58 KDa
Source organism: Burkholderia cepacia
Expression system: Escherichia coli
UniProt:
  • Canonical: P16932 (Residues: 1-433; Coverage: 100%)
Gene name: dgdA
Sequence domains: Aminotransferase class-III
Structure domains:

Ligands and Environments


Cofactor: Ligand PLP 1 x PLP
3 bound ligands:
Ligand NA 1 x NA
Ligand CA 1 x CA
Ligand MES 1 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER
Spacegroup: P6422
Unit cell:
a: 150.553Å b: 150.553Å c: 84.703Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.219 0.219 0.277
Expression system: Escherichia coli

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