Function and Biology Details
Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
DNA topoisomerase 4 subunit A (preferred)
PDBe Complex ID:
PDB-CPX-142726 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA topoisomerase 4 subunit A
Molecule details ›
Chains: A, B
Length: 256 amino acids
Theoretical weight: 27.6 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: DNA gyrase C-terminal domain, beta-propeller
Length: 256 amino acids
Theoretical weight: 27.6 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P0AFI2 (Residues: 497-752; Coverage: 34%)
Sequence domains: DNA gyrase C-terminal domain, beta-propeller
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.3.1
Spacegroup:
P1
Expression system: Escherichia coli BL21
