› 214d

Solution NMR

THE SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING A SINGLE 2'-O-METHYL-BETA-D-ARAT

Released:
DOI: 10.2210/pdb214d/pdb
PDB entry 214d coloured by chain, ensemble of 40 models, front view.
PDB entry 214d coloured by chain, ensemble of 40 models, side view.
PDB entry 214d coloured by chain, ensemble of 40 models, top view.
Source organism: Synthetic construct
Primary publication:
Structure of a DNA duplex containing a single 2'-O-methyl-beta-D-araT: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement.
Gotfredsen CH, Spielmann HP, Wengel J, Jacobsen JP
Bioconjug Chem 7 680-8
PMID: 8950487

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114983 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*CP*GP*CP*AP*TP*AP*TP*AP*GP*CP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 11 nucleotides
Theoretical weight: 3.32 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*GP*GP*CP*TP*AP*(T41)P*AP*TP*GP*CP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.42 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand T41 1 x T41

Experiments and Validation Details

Entry percentile scores
Refinement method: MOLECULAR DYNAMICS, MATRIX RELAXATION
Expression system: Not provided

Quick links

Citations

7 citation in other articles

The solution structure of a locked nucleic acid (LNA) hybridized to DNA.
Nielsen et al. (1999)
6 more

2 mentions without citation

Tetrazoles via Multicomponent Reactions.
Neochoritis et al. (2019)
1 more