› 284d

X-ray diffraction
1.1Å resolution

THE BI-LOOP, A NEW GENERAL FOUR-STRANDED DNA MOTIF

Released:
DOI: 10.2210/pdb284d/pdb
PDB entry 284d coloured by chain, front view.
PDB entry 284d coloured by chain, side view.
PDB entry 284d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The bi-loop, a new general four-stranded DNA motif.
Salisbury SA, Wilson SE, Powell HR, Kennard O, Lubini P, Sheldrick GM, Escaja N, Alazzouzi E, Grandas A, Pedroso E
Proc Natl Acad Sci U S A 94 5515-8 (1997)
PMID: 9159103

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115040 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-CD(*P*AP*TP*TP*CP*AP*TP*TP*C)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 8 nucleotides
Theoretical weight: 2.38 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand BA 11 x BA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 22.844Å b: 27.676Å c: 55.37Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 not available not available
Expression system: Not provided

Quick links

Citations

5 review citations

Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
Patel et al. (2007)
4 more

4 mentions without citation

Proton-coupled electron transfer.
Huynh et al. (2007)
3 more