› 2a15

X-ray diffraction
1.68Å resolution

X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution

Released:
DOI: 10.2210/pdb2a15/pdb
PDB entry 2a15 coloured by chain, front view.
PDB entry 2a15 coloured by chain, side view.
PDB entry 2a15 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase.
Cherney MM, Garen CR, James MN
Biochim Biophys Acta 1784 1625-32 (2008)
PMID: 18589008

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159819 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear transport factor 2 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.26 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P71817 (Residues: 1-139; Coverage: 100%)
Gene name: MT0785
Sequence domains: Nuclear transport factor 2 (NTF2) domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

1 bound ligand:
Ligand NCA 1 x NCA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P3212
Unit cell:
a: 55.6Å b: 55.6Å c: 104.74Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.176 0.207
Expression system: Escherichia coli

Quick links

Citations

4 citation in other articles

High-performance prediction of functional residues in proteins with machine learning and computed input features.
Somarowthu et al. (2011)
3 more

2 mentions without citation

DG-AMMOS: a new tool to generate 3d conformation of small molecules using distance geometry and automated molecular mechanics optimization for in silico screening.
Lagorce et al. (2009)
1 more