› 2a2f

X-ray diffraction
2.5Å resolution

Crystal Structure of Sec15 C-terminal domain

Released:
DOI: 10.2210/pdb2a2f/pdb
PDB entry 2a2f coloured by chain, front view.
PDB entry 2a2f coloured by chain, side view.
PDB entry 2a2f coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo.
Wu S, Mehta SQ, Pichaud F, Bellen HJ, Quiocho FA
Nat Struct Mol Biol 12 879-85 (2005)
PMID: 16155582

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-194227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exocyst complex component 6 Chain: X
Molecule details ›
Chain: X
Length: 325 amino acids
Theoretical weight: 37.96 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9VDE6 (Residues: 381-699; Coverage: 42%)
Gene names: CG7034, Sec15
Sequence domains: Exocyst complex subunit Sec15 C-terminal
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1, null
Spacegroup: C2221
Unit cell:
a: 80.5Å b: 93.9Å c: 123.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.243 0.276
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

55 review citations

Role of Rab GTPases in membrane traffic and cell physiology.
Hutagalung et al. (2011)
54 more

12 mentions without citation

Exposing the Elusive Exocyst Structure.
Lepore et al. (2018)
11 more