› 2a6b

X-ray diffraction
1.7Å resolution

Crystal structure of a putative transcriptional regulator of the tena family (spr0628) from streptococcus pneumoniae r6 at 1.70 A resolution

Released:
DOI: 10.2210/pdb2a6b/pdb
PDB entry 2a6b coloured by chain, front view.
PDB entry 2a6b coloured by chain, side view.
PDB entry 2a6b coloured by chain, top view.
Source organism: Streptococcus pneumoniae R6
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
4-amino-5-aminomethyl-2-methylpyrimidine + H(2)O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + ammonia
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184158 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminopyrimidine aminohydrolase Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 27.34 KDa
Source organism: Streptococcus pneumoniae R6
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8DQK6 (Residues: 1-222; Coverage: 100%)
Gene name: spr0628
Sequence domains: TENA/THI-4/PQQC family
Structure domains: Heme oxygenase-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2, SSRL BEAMLINE BL1-5
Spacegroup: P4212
Unit cell:
a: 119.908Å b: 119.908Å c: 47.105Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.155 0.175
Expression system: Escherichia coli

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