› 2adz

Solution NMR

solution structure of the joined PH domain of alpha1-syntrophin

Released:
DOI: 10.2210/pdb2adz/pdb
PDB entry 2adz coloured by chain, ensemble of 20 models, front view.
PDB entry 2adz coloured by chain, ensemble of 20 models, side view.
PDB entry 2adz coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin.
Yan J, Wen W, Xu W, Long JF, Adams ME, Froehner SC, Zhang M
EMBO J 24 3985-95 (2005)
PMID: 16252003

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178874 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-1-syntrophin Chain: A
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 18.64 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q61234 (Residues: 2-264; Coverage: 35%)
Gene names: Snt1, Snta1
Sequence domains: PH domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density.
Feng et al. (2009)
8 more

4 mentions without citation

Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin.
Yan et al. (2005)
3 more