› 2aem

X-ray diffraction
2.8Å resolution

Crystal Structures of the MthK RCK Domain

Released:
DOI: 10.2210/pdb2aem/pdb
PDB entry 2aem coloured by chain, front view.
PDB entry 2aem coloured by chain, side view.
PDB entry 2aem coloured by chain, top view.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Structures of the MthK RCK domain and the effect of Ca2+ on gating ring stability.
Dong J, Shi N, Berke I, Chen L, Jiang Y
J Biol Chem 280 41716-24 (2005)
PMID: 16227203

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127897 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-gated potassium channel MthK Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 25.91 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O27564 (Residues: 107-336; Coverage: 69%)
Gene names: MTH_1520, mthK
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: R32
Unit cell:
a: 164.88Å b: 164.88Å c: 82.852Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.224 0.262
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Potassium and sodium transport in non-animal cells: the Trk/Ktr/HKT transporter family.
Corratgé-Faillie et al. (2010)
4 more

3 mentions without citation

KTN (RCK) domains regulate K+ channels and transporters by controlling the dimer-hinge conformation.
Roosild et al. (2009)
2 more