2agj

X-ray diffraction
2.6Å resolution

Crystal Structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-134957 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.37 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q6PJF2 (Residues: 21-235; Coverage: 100%)
Gene name: IGK@
Sequence domains:
Structure domains: Immunoglobulins
Immunoglobulin heavy constant mu Chain: H
Molecule details ›
Chain: H
Length: 226 amino acids
Theoretical weight: 24.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01871 (Residues: 1-106; Coverage: 22%)
Gene name: IGHM
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: I222
Unit cell:
a: 82.433Å b: 103.653Å c: 138.715Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.219 0.279