2agw

X-ray diffraction
1.45Å resolution

Crystal structure of tryptamine-reduced aromatic amine dehydrogenase (AADH) from Alcaligenes faecalis in complex with tryptamine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-160926 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Aralkylamine dehydrogenase light chain Chains: D, H
Molecule details ›
Chains: D, H
Length: 135 amino acids
Theoretical weight: 14.52 KDa
Source organism: Alcaligenes faecalis
UniProt:
  • Canonical: P84887 (Residues: 48-182; Coverage: 100%)
Gene name: aauA
Sequence domains: Methylamine dehydrogenase, L chain
Structure domains: Methylamine/Aralkylamine dehydrogenase light chain
Aralkylamine dehydrogenase heavy chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 361 amino acids
Theoretical weight: 40.02 KDa
Source organism: Alcaligenes faecalis
UniProt:
  • Canonical: P84888 (Residues: 30-389; Coverage: 99%)
Gene name: aauB
Sequence domains: Methylamine dehydrogenase heavy chain (MADH)
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 70.998Å b: 88.749Å c: 81.149Å
α: 90° β: 89.99° γ: 90°
R-values:
R R work R free
0.165 0.163 0.195