› 2aoz

X-ray diffraction
2.08Å resolution

Crystal structure of the myotoxin-II from Atropoides nummifer venom

Released:
DOI: 10.2210/pdb2aoz/pdb
PDB entry 2aoz coloured by chain, front view.
PDB entry 2aoz coloured by chain, side view.
PDB entry 2aoz coloured by chain, top view.
Source organism: Atropoides nummifer
Primary publication:
Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom.
Murakami MT, Melo CC, Angulo Y, Lomonte B, Arni RK
Acta Crystallogr Sect F Struct Biol Cryst Commun 62 423-6 (2006)
PMID: 16682766

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160655 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Basic phospholipase A2 homolog Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.73 KDa
Source organism: Atropoides nummifer
UniProt:
  • Canonical: P82950 (Residues: 1-121; Coverage: 100%)
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P43212
Unit cell:
a: 68.939Å b: 68.939Å c: 64.069Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.219 0.275

Quick links

Citations

2 citation in other articles

Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A₂ class.
dos Santos et al. (2011)
1 more

3 mentions without citation

Virtual Screening Approaches towards the Discovery of Toll-Like Receptor Modulators.
Pérez-Regidor et al. (2016)
2 more