› 2aq5

X-ray diffraction
1.75Å resolution

Crystal Structure of Murine Coronin-1

Released:
DOI: 10.2210/pdb2aq5/pdb
PDB entry 2aq5 coloured by chain, front view.
PDB entry 2aq5 coloured by chain, side view.
PDB entry 2aq5 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes.
Appleton BA, Wu P, Wiesmann C
Structure 14 87-96 (2006)
PMID: 16407068

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131604 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coronin-1A Chain: A
Molecule details ›
Chain: A
Length: 402 amino acids
Theoretical weight: 44.5 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O89053 (Residues: 1-402; Coverage: 87%)
Gene names: Coro1, Coro1a
Sequence domains:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

No bound ligands
2 modified residues:
Ligand CME 1 x CME
Ligand CSO 4 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 52.996Å b: 80.443Å c: 88.208Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.158 0.192
Expression system: Spodoptera frugiperda

Quick links

Citations

12 review citations

Unraveling the enigma: progress towards understanding the coronin family of actin regulators.
Chan et al. (2011)
11 more

11 mentions without citation

Towards a molecular understanding of the apicomplexan actin motor: on a road to novel targets for malaria remedies?
Kumpula et al. (2015)
10 more