› 2asc

X-ray diffraction
1.1Å resolution

Scorpion toxin LQH-alpha-IT

Released:
DOI: 10.2210/pdb2asc/pdb
PDB entry 2asc coloured by chain, front view.
PDB entry 2asc coloured by chain, side view.
PDB entry 2asc coloured by chain, top view.
Source organism: Leiurus quinquestriatus
Entry authors: Kahn R, Karbat I, Gurevitz M, Frolow F

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148149 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-insect toxin LqhaIT Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.4 KDa
Source organism: Leiurus quinquestriatus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P17728 (Residues: 20-82; Coverage: 96%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

8 bound ligands:
Ligand DR8 1 x DR8
Ligand DR0 1 x DR0
Ligand CL 3 x CL
Ligand NO3 1 x NO3
Ligand K 1 x K
Ligand EDO 5 x EDO
Ligand MOH 3 x MOH
Ligand EOH 3 x EOH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: F432
Unit cell:
a: 129.714Å b: 129.714Å c: 129.714Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.131 0.13 0.138
Expression system: Escherichia coli BL21

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