› 2avp

X-ray diffraction
2.04Å resolution

Crystal structure of an 8 repeat consensus TPR superhelix

Released:
DOI: 10.2210/pdb2avp/pdb
PDB entry 2avp coloured by chain, front view.
PDB entry 2avp coloured by chain, side view.
PDB entry 2avp coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure and stability of designed TPR protein superhelices: unusual crystal packing and implications for natural TPR proteins.
Kajander T, Cortajarena AL, Mochrie S, Regan L
Acta Crystallogr D Biol Crystallogr 63 800-11 (2007)
PMID: 17582171

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162630 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
synthetic consensus TPR protein Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 8.23 KDa
Source organism: Synthetic construct
Expression system: Not provided
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

1 bound ligand:
Ligand CD 2 x CD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P41212
Unit cell:
a: 54.245Å b: 54.245Å c: 71.782Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.201 0.241
Expression system: Not provided

Quick links

Citations

4 review citations

Structural and functional discussion of the tetra-trico-peptide repeat, a protein interaction module.
Zeytuni et al. (2012)
3 more

8 mentions without citation

Design and characterization of structured protein linkers with differing flexibilities.
Klein et al. (2014)
7 more