› 2ayi

X-ray diffraction
3.7Å resolution

Wild-type AmpT from Thermus thermophilus

Released:
DOI: 10.2210/pdb2ayi/pdb
PDB entry 2ayi coloured by chain, front view.
PDB entry 2ayi coloured by chain, side view.
PDB entry 2ayi coloured by chain, top view.
Source organism: Thermus thermophilus
Primary publication:
Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan.
Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M
J Mol Biol 354 403-12 (2005)
PMID: 16242715

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminopeptidase T Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 408 amino acids
Theoretical weight: 45.08 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: P42778 (Residues: 1-408; Coverage: 100%)
Gene name: TTHA1152
Sequence domains: Thermophilic metalloprotease (M29)
Structure domains: Thermophilic metalloprotease (M29)

Ligands and Environments

1 bound ligand:
Ligand ZN 10 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P42
Unit cell:
a: 246.472Å b: 246.472Å c: 51.135Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.308 0.308 0.321
Expression system: Escherichia coli

Quick links

Citations

7 citation in other articles

Intrinsic motions along an enzymatic reaction trajectory.
Henzler-Wildman et al. (2007)
6 more

3 mentions without citation

Aminopeptidase T of M29 Family Acts as A Novel Intracellular Virulence Factor for Listeria monocytogenes Infection.
Cheng et al. (2015)
2 more