Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Telomerase reverse transcriptase (preferred)
PDBe Complex ID:
PDB-CPX-131268 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomerase reverse transcriptase
Molecule details ›
Chains: A, B, C
Length: 199 amino acids
Theoretical weight: 23.62 KDa
Source organism: Tetrahymena thermophila
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Telomerase reverse transcriptase TEN domain
Length: 199 amino acids
Theoretical weight: 23.62 KDa
Source organism: Tetrahymena thermophila
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O77448 (Residues: 2-191; Coverage: 17%)
Sequence domains: Telomerase reverse transcriptase TEN domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.2.1
Spacegroup:
P31
Expression system: Escherichia coli BL21(DE3)
