› 2b5b

Solution NMR

A reptilian defensin with anti-bacterial and anti-viral activity

Released:
DOI: 10.2210/pdb2b5b/pdb
PDB entry 2b5b coloured by chain, ensemble of 10 models, front view.
PDB entry 2b5b coloured by chain, ensemble of 10 models, side view.
PDB entry 2b5b coloured by chain, ensemble of 10 models, top view.
Source organism: Caretta caretta
Primary publication:
Small cationic protein from a marine turtle has beta-defensin-like fold and antibacterial and antiviral activity.
Chattopadhyay S, Sinha NK, Banerjee S, Roy D, Chattopadhyay D, Roy S
Proteins 64 524-31 (2006)
PMID: 16700051

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143191 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Defensin-like turtle egg white protein TEWP Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 4.09 KDa
Source organism: Caretta caretta
UniProt:
  • Canonical: P0CAP0 (Residues: 1-36; Coverage: 100%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics, energy minimization and molecular dynamics at constant temperature, time and volume

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Citations

11 review citations

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria.
Ageitos et al. (2017)
10 more