› 2baf

Solution NMR

Bovine Fibrinogen alpha-C Domain

Released:
DOI: 10.2210/pdb2baf/pdb
PDB entry 2baf coloured by chain, ensemble of 20 models, front view.
PDB entry 2baf coloured by chain, ensemble of 20 models, side view.
PDB entry 2baf coloured by chain, ensemble of 20 models, top view.
Source organism: Bos taurus
Primary publication:
Identification of an ordered compact structure within the recombinant bovine fibrinogen alphaC-domain fragment by NMR.
Burton RA, Tsurupa G, Medved L, Tjandra N
Biochemistry 45 2257-66 (2006)
PMID: 16475814

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136030 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibrinogen alpha chain Chain: A
Molecule details ›
Chain: A
Length: 166 amino acids
Theoretical weight: 18.15 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P02672 (Residues: 406-570; Coverage: 28%)
Gene name: FGA
Sequence domains: Fibrinogen alpha C domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Fibrin clot structure and function: a role in the pathophysiology of arterial and venous thromboembolic diseases.
Undas et al. (2011)
7 more

2 mentions without citation

Fibrin(ogen) as a Therapeutic Target: Opportunities and Challenges.
Gaule et al. (2021)
1 more