› 2bbh

X-ray diffraction
1.85Å resolution

X-ray structure of T.maritima CorA soluble domain

Released:
DOI: 10.2210/pdb2bbh/pdb
PDB entry 2bbh coloured by chain, front view.
PDB entry 2bbh coloured by chain, side view.
PDB entry 2bbh coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Crystal structure of the CorA Mg2+ transporter.
Lunin VV, Dobrovetsky E, Khutoreskaya G, Zhang R, Joachimiak A, Doyle DA, Bochkarev A, Maguire ME, Edwards AM, Koth CM
Nature 440 833-7 (2006)
PMID: 16598263

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-194569 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cobalt/magnesium transport protein CorA Chain: A
Molecule details ›
Chain: A
Length: 269 amino acids
Theoretical weight: 32.17 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9WZ31 (Residues: 1-266; Coverage: 76%)
Gene names: TM_0561, corA
Sequence domains: CorA-like Mg2+ transporter protein
Structure domains: CorA soluble domain-like

Ligands and Environments

3 bound ligands:
Ligand DMU 4 x DMU
Ligand NA 1 x NA
Ligand MG 1 x MG
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P41212
Unit cell:
a: 77.995Å b: 77.995Å c: 101.609Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.233
Expression system: Escherichia coli BL21

Quick links

Citations

30 review citations

Rationalizing membrane protein overexpression.
Wagner et al. (2006)
29 more

6 mentions without citation

A structural basis for Mg2+ homeostasis and the CorA translocation cycle.
Payandeh et al. (2006)
5 more