Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Capsid protein VP3 (preferred)
PDBe Complex ID:
PDB-CPX-136689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Viral protein genome-linked
Molecule details ›
Chain: A
Length: 22 amino acids
Theoretical weight: 2.36 KDa
Source organism: Human poliovirus 1 Mahoney
Expression system: Not provided
UniProt:
Length: 22 amino acids
Theoretical weight: 2.36 KDa
Source organism: Human poliovirus 1 Mahoney
Expression system: Not provided
UniProt:
- Canonical:
P03300 (Residues: 1544-1565; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
automatic NOE assignment in combination with distance geometry
Expression system: Not provided
