› 2bbx

Solution NMR

NMR solution structure of the TSR domain of malaria TRAP protein

Released:
DOI: 10.2210/pdb2bbx/pdb
PDB entry 2bbx coloured by chain, ensemble of 20 models, front view.
PDB entry 2bbx coloured by chain, ensemble of 20 models, side view.
PDB entry 2bbx coloured by chain, ensemble of 20 models, top view.
Source organism: Plasmodium falciparum
Primary publication:
The layered fold of the TSR domain of P. falciparum TRAP contains a heparin binding site.
Tossavainen H, Pihlajamaa T, Huttunen TK, Raulo E, Rauvala H, Permi P, Kilpeläinen I
Protein Sci 15 1760-8 (2006)
PMID: 16815922

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147840 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thrombospondin-related anonymous protein Chain: A
Molecule details ›
Chain: A
Length: 49 amino acids
Theoretical weight: 5.45 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P16893 (Residues: 241-288; Coverage: 9%)
Gene name: TRAP
Sequence domains: Thrombospondin type 1 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

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Citations

15 review citations

Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria.
Beeson et al. (2016)
14 more

14 mentions without citation

The CCN family of proteins: structure-function relationships.
Holbourn et al. (2008)
13 more