› 2be4

X-ray diffraction
2.1Å resolution

X-RAY STRUCTURE AN EF-HAND PROTEIN FROM DANIO RERIO Dr.36843

Released:
DOI: 10.2210/pdb2be4/pdb
PDB entry 2be4 coloured by chain, front view.
PDB entry 2be4 coloured by chain, side view.
PDB entry 2be4 coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
X-ray structure of Danio rerio secretagogin: A hexa-EF-hand calcium sensor.
Bitto E, Bingman CA, Bittova L, Frederick RO, Fox BG, Phillips GN
Proteins 76 477-83 (2009)
PMID: 19241471

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178507 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Secretagogin Chain: A
Molecule details ›
Chain: A
Length: 272 amino acids
Theoretical weight: 32.05 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5XJX1 (Residues: 2-272; Coverage: 100%)
Gene names: scgn, zgc:100843
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 47.884Å b: 52.748Å c: 114.364Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.176 0.253
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The renaissance of Ca2+-binding proteins in the nervous system: secretagogin takes center stage.
Alpár et al. (2012)
8 other articles

6 mentions without citation

X-ray structure of Danio rerio secretagogin: A hexa-EF-hand calcium sensor.
Bitto et al. (2009)
5 more