› 2bhv

X-ray diffraction
3Å resolution

Structure of ComB10 of the Com Type IV secretion system of Helicobacter pylori

Released:
DOI: 10.2210/pdb2bhv/pdb
PDB entry 2bhv coloured by chain, front view.
PDB entry 2bhv coloured by chain, side view.
PDB entry 2bhv coloured by chain, top view.
Source organism: Helicobacter pylori
Primary publication:
Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori.
Terradot L, Bayliss R, Oomen C, Leonard GA, Baron C, Waksman G
Proc Natl Acad Sci U S A 102 4596-601 (2005)
PMID: 15764702

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127686 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TrbI protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 246 amino acids
Theoretical weight: 27.18 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O24883 (Residues: 1-233; Coverage: 100%)
Gene name: HP_0042
Sequence domains: Bacterial conjugation TrbI-like protein
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 69.735Å b: 139.411Å c: 168.442Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.259 0.257 0.293
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

36 review citations

Biogenesis, architecture, and function of bacterial type IV secretion systems.
Christie et al. (2005)
35 more

2 mentions without citation

Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori.
Terradot et al. (2005)
1 more