› 2bkf

X-ray diffraction
1.56Å resolution

Structure of the PB1 domain of NBR1

Released:
DOI: 10.2210/pdb2bkf/pdb
PDB entry 2bkf coloured by chain, front view.
PDB entry 2bkf coloured by chain, side view.
PDB entry 2bkf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the PB1 domain of NBR1.
Müller S, Kursula I, Zou P, Wilmanns M
FEBS Lett 580 341-4 (2006)
PMID: 16376336

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172040 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Next to BRCA1 gene 1 protein Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 9.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14596 (Residues: 1-85; Coverage: 9%)
Gene names: 1A13B, KIAA0049, M17S2, MIG19, NBR1
Sequence domains: PB1 domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P6322
Unit cell:
a: 100.612Å b: 100.612Å c: 42.16Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.199 0.226
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Cell signaling and function organized by PB1 domain interactions.
Moscat et al. (2006)
1 more

4 mentions without citation

Structure biology of selective autophagy receptors.
Kim et al. (2016)
3 more