2bpe

X-ray diffraction
2.25Å resolution

STRUCTURE OF MURINE DECTIN-1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-180274 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type lectin domain family 7 member A Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 16.23 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6QLQ4 (Residues: 113-244; Coverage: 54%)
Gene names: Bgr, Clec7a, Clecsf12, Dectin1
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P3221
Unit cell:
a: 84.685Å b: 84.685Å c: 117.686Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.188 0.231
Expression system: Escherichia coli BL21(DE3)