› 2btu

X-ray diffraction
2.31Å resolution

Crystal structure of Phosphoribosylformylglycinamidine cyclo-ligase from Bacillus Anthracis at 2.3A resolution.

Released:
DOI: 10.2210/pdb2btu/pdb
PDB entry 2btu coloured by chain, front view.
PDB entry 2btu coloured by chain, side view.
PDB entry 2btu coloured by chain, top view.
Source organism: Bacillus anthracis
Entry authors: Moroz OV, Blagova EV, Levdikov VM, Fogg MJ, Lebedev AA, Brannigan JA, Wilkinson AJ, Wilson KS

Function and Biology Details

Reaction catalysed: 
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182624 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoribosylformylglycinamidine cyclo-ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 346 amino acids
Theoretical weight: 37.3 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q81ZH0 (Residues: 1-346; Coverage: 100%)
Gene names: BAS0283, BA_0296, GBAA_0296, purM
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P41
Unit cell:
a: 89.49Å b: 89.49Å c: 88.117Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 not available 0.249
Expression system: Escherichia coli BL21(DE3)

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