› 2bve

X-ray diffraction
2.2Å resolution

Structure of the N-terminal of Sialoadhesin in complex with 2-Phenyl- Prop5Ac

Released:
DOI: 10.2210/pdb2bve/pdb
Model geometry
Fit model/data
Data not deposited
PDB entry 2bve coloured by chain, front view.
PDB entry 2bve coloured by chain, side view.
PDB entry 2bve coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.
Zaccai NR, May AP, Robinson RC, Burtnick LD, Crocker PR, Brossmer R, Kelm S, Jones EY
J Mol Biol 365 1469-79 (2007)
PMID: 17137591

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178923 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sialoadhesin Chains: A, B
Molecule details ›
Chains: A, B
Length: 119 amino acids
Theoretical weight: 13.32 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q62230 (Residues: 20-138; Coverage: 7%)
Gene names: Sa, Siglec1, Sn
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand PH5 2 x PH5
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P212121
Unit cell:
a: 31.974Å b: 70.961Å c: 102.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.201 0.27
Expression system: Cricetulus griseus

Quick links

Citations

6 review citations

Siglecs and immune regulation.
Pillai et al. (2012)
5 more

2 mentions without citation

Conformational changes in redox pairs of protein structures.
Fan et al. (2009)
1 more