› 2bx6

X-ray diffraction
2.1Å resolution

Crystal Structure of the human Retinitis Pigmentosa protein 2 (RP2)

Released:
DOI: 10.2210/pdb2bx6/pdb
PDB entry 2bx6 coloured by chain, front view.
PDB entry 2bx6 coloured by chain, side view.
PDB entry 2bx6 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human retinitis pigmentosa 2 protein and its interaction with Arl3.
Kühnel K, Veltel S, Schlichting I, Wittinghofer A
Structure 14 367-78 (2006)
PMID: 16472755

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131105 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein XRP2 Chain: A
Molecule details ›
Chain: A
Length: 350 amino acids
Theoretical weight: 39.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O75695 (Residues: 1-350; Coverage: 100%)
Gene name: RP2
Sequence domains: Tubulin binding cofactor C
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P3221
Unit cell:
a: 81.3Å b: 81.3Å c: 106.12Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.197 0.235
Expression system: Escherichia coli BL21

Quick links

Citations

10 review citations

Regulation of small GTPases by GEFs, GAPs, and GDIs.
Cherfils et al. (2013)
9 more

5 mentions without citation

NME/NM23/NDPK and Histidine Phosphorylation.
Adam et al. (2020)
4 more