Function and Biology Details
Reaction catalysed:
[Biotin carboxyl-carrier protein]-N(6)-carboxybiotinyl-L-lysine + acetyl-CoA = [biotin carboxyl-carrier protein]-N(6)-biotinyl-L-lysine + malonyl-CoA
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162078 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta5 subunit
Molecule details ›
Chains: A, B, C, D, E, F
Length: 548 amino acids
Theoretical weight: 59.36 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
Sequence domains: Carboxyl transferase domain
Structure domains: 2-enoyl-CoA Hydratase; Chain A, domain 1
Length: 548 amino acids
Theoretical weight: 59.36 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
- Canonical:
P9WQH7 (Residues: 1-548; Coverage: 100%)
Sequence domains: Carboxyl transferase domain
Structure domains: 2-enoyl-CoA Hydratase; Chain A, domain 1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE BM14
Spacegroup:
P41212
Expression system: Escherichia coli
