› 2c08

X-ray diffraction
2.9Å resolution

Rat endophilin A1 BAR domain

Released:
DOI: 10.2210/pdb2c08/pdb
PDB entry 2c08 coloured by chain, front view.
PDB entry 2c08 coloured by chain, side view.
PDB entry 2c08 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Mechanism of endophilin N-BAR domain-mediated membrane curvature.
Gallop JL, Jao CC, Kent HM, Butler PJ, Evans PR, Langen R, McMahon HT
EMBO J 25 2898-910 (2006)
PMID: 16763559

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128654 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endophilin-A1 Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 24.03 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O35179 (Residues: 25-247; Coverage: 58%)
Gene names: Sh3d2a, Sh3gl2, Sh3p4
Sequence domains: BAR domain
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: I41
Unit cell:
a: 126.578Å b: 126.578Å c: 101.226Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.28 0.279 0.295
Expression system: Escherichia coli BL21

Quick links

Citations

109 review citations

Membrane recognition by phospholipid-binding domains.
Lemmon MA. (2008)
108 more

15 mentions without citation

A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis.
Taylor et al. (2011)
14 more