› 2c3e

X-ray diffraction
2.8Å resolution

The bovine mitochondrial ADP-ATP carrier

Released:
DOI: 10.2210/pdb2c3e/pdb
PDB entry 2c3e coloured by chain, front view.
PDB entry 2c3e coloured by chain, side view.
PDB entry 2c3e coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structural basis for lipid-mediated interactions between mitochondrial ADP/ATP carrier monomers.
Nury H, Dahout-Gonzalez C, Trézéguet V, Lauquin G, Brandolin G, Pebay-Peyroula E
FEBS Lett 579 6031-6 (2005)
PMID: 16226253

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136100 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP/ATP translocase 1 Chain: A
Molecule details ›
Chain: A
Length: 297 amino acids
Theoretical weight: 32.88 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02722 (Residues: 2-298; Coverage: 100%)
Gene names: AAC1, ANT1, SLC25A4
Sequence domains: Mitochondrial carrier protein
Structure domains: Mitochondrial carrier domain

Ligands and Environments

2 bound ligands:
Ligand CXT 1 x CXT
Ligand CDL 3 x CDL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: C2221
Unit cell:
a: 76.246Å b: 110.752Å c: 89.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.25 0.281

Quick links

Citations

36 review citations

Lipids of mitochondria.
Horvath et al. (2013)
35 more

38 mentions without citation

The SLC25 Mitochondrial Carrier Family: Structure and Mechanism.
Ruprecht et al. (2020)
37 more