› 2cdy

X-ray diffraction
2Å resolution

Manganese Superoxide Dismutase (Mn-SOD) from Deinococcus radiodurans

Released:
DOI: 10.2210/pdb2cdy/pdb
PDB entry 2cdy coloured by chain, front view.
PDB entry 2cdy coloured by chain, side view.
PDB entry 2cdy coloured by chain, top view.
Source organism: Deinococcus radiodurans R1
Primary publication:
Structure of the manganese superoxide dismutase from Deinococcus radiodurans in two crystal forms.
Dennis RJ, Micossi E, McCarthy J, Moe E, Gordon EJ, Kozielski-Stuhrmann S, Leonard GA, McSweeney S
Acta Crystallogr Sect F Struct Biol Cryst Commun 62 325-9 (2006)
PMID: 16582477

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193284 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Mn] Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 231 amino acids
Theoretical weight: 25.98 KDa
Source organism: Deinococcus radiodurans R1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9RUV2 (Residues: 1-211; Coverage: 100%)
Gene names: DR_1279, sodA
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MN 4 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 43.577Å b: 87.1Å c: 116.418Å
α: 90° β: 92.1° γ: 90°
R-values:
R R work R free
0.176 0.173 0.221
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Superoxide Anion Chemistry-Its Role at the Core of the Innate Immunity.
Andrés et al. (2023)
3 other articles

3 mentions without citation

Structural features and functional implications of proteins enabling the robustness of Deinococcus radiodurans.
Chen et al. (2020)
2 more