› 2clb

X-ray diffraction
2.4Å resolution

The structure of the DPS-like protein from Sulfolobus solfataricus reveals a bacterioferritin-like di-metal binding site within a Dps- like dodecameric assembly

Released:
DOI: 10.2210/pdb2clb/pdb
Model geometry
Fit model/data
PDB entry 2clb coloured by chain, front view.
PDB entry 2clb coloured by chain, side view.
PDB entry 2clb coloured by chain, top view.
Source organism: Saccharolobus solfataricus P2
Primary publication:
Structure of the DPS-like protein from Sulfolobus solfataricus reveals a bacterioferritin-like dimetal binding site within a DPS-like dodecameric assembly.
Gauss GH, Benas P, Wiedenheft B, Young M, Douglas T, Lawrence CM
Biochemistry 45 10815-27 (2006)
PMID: 16953567

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA protection during starvation protein Chains: A, B, C, D, M, N, O, P
Molecule details ›
Chains: A, B, C, D, M, N, O, P
Length: 188 amino acids
Theoretical weight: 22.04 KDa
Source organism: Saccharolobus solfataricus P2
Expression system: Escherichia coli
UniProt:
  • Canonical: P95855 (Residues: 1-188; Coverage: 100%)
Gene names: C06008, SSO2079, dps
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

2 bound ligands:
Ligand ZN 8 x ZN
Ligand FE 8 x FE
1 modified residue:
Ligand MSE 40 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: I213
Unit cell:
a: 212.928Å b: 212.928Å c: 212.928Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.222
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Ferritin: the protein nanocage and iron biomineral in health and in disease.
Theil EC. (2013)
6 more

4 mentions without citation

Protein cage assembly across multiple length scales.
Aumiller et al. (2018)
3 more