› 2coe

Solution NMR

Solution structure of BRCT domain of terminal deoxynucleotidyltransferase

Released:
DOI: 10.2210/pdb2coe/pdb
PDB entry 2coe coloured by chain, ensemble of 20 models, front view.
PDB entry 2coe coloured by chain, ensemble of 20 models, side view.
PDB entry 2coe coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Nagashima T, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137369 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA nucleotidylexotransferase Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 12.9 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04053 (Residues: 19-125; Coverage: 21%)
Gene names: DNTT, TDT
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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