› 2cp8

Solution NMR

Solution structure of the RSGI RUH-046, a UBA domain from human Next to BRCA1 gene 1 protein (KIAA0049 protein) R923H variant

Released:
DOI: 10.2210/pdb2cp8/pdb
PDB entry 2cp8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2cp8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2cp8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Ohashi W, Hirota H, Yamazaki T, Muto Y, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172040 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Next to BRCA1 gene 1 protein Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 5.83 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q14596 (Residues: 916-956; Coverage: 4%)
Gene names: 1A13B, KIAA0049, M17S2, MIG19, NBR1
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated anneling, torsion angle dynamics
Expression system: Not provided

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