Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
ATP + H(2)O = ADP + phosphate
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Reovirus, outer capsid sigma-3 domain superfamily
- Reovirus, outer capsid sigma 3
- Mu1 membrane penetration protein, domain IV
- Mu1 membrane penetration protein, domain III
- Mu1 membrane penetration protein, domain II
- Mu1 membrane penetration protein, domain I
- Mu1/VP4 superfamily
- Outer capsid protein Mu1/VP4
18 more domains
Structure domains:
Structure analysis Details
Assembly composition:
hetero 1620-mer (preferred)
PDBe Complex ID:
PDB-CPX-139845 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Outer capsid protein mu-1
Molecule details ›
Chains: A, B, C, J, K, L, P, Q, R, T
Length: 708 amino acids
Theoretical weight: 76.35 KDa
Source organism: Mammalian orthoreovirus 1 Lang
UniProt:
Sequence domains: Reovirus major virion structural protein Mu-1/Mu-1C (M2)
Length: 708 amino acids
Theoretical weight: 76.35 KDa
Source organism: Mammalian orthoreovirus 1 Lang
UniProt:
- Canonical:
P11077 (Residues: 1-708; Coverage: 100%)
Sequence domains: Reovirus major virion structural protein Mu-1/Mu-1C (M2)
Outer capsid protein sigma-3
Molecule details ›
Chains: D, E, F, G, H, I, M, N, O, S
Length: 365 amino acids
Theoretical weight: 41.24 KDa
Source organism: Mammalian orthoreovirus 1 Lang
UniProt:
Sequence domains: Reovirus outer capsid protein, Sigma 3
Length: 365 amino acids
Theoretical weight: 41.24 KDa
Source organism: Mammalian orthoreovirus 1 Lang
UniProt:
- Canonical: P07939 (Residues: 1-365; Coverage: 100%)
Sequence domains: Reovirus outer capsid protein, Sigma 3
Outer capsid protein lambda-2
Inner capsid protein lambda-1
Inner capsid protein sigma-2
RNA-directed RNA polymerase lambda-3
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this EM entry.
Resolution:
7Å
