› 2ctz

X-ray diffraction
2.6Å resolution

Crystal structure of o-acetyl homoserine sulfhydrylase from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb2ctz/pdb
PDB entry 2ctz coloured by chain, front view.
PDB entry 2ctz coloured by chain, side view.
PDB entry 2ctz coloured by chain, top view.
Source organism: Thermus thermophilus
Entry authors: Imagawa T, Kousumi Y, Tsuge H, Utsunomiya H, Ebihara A, Nakagawa N, Yokoyama S, Kuramitsu S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-178075 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
O-acetyl-L-homoserine sulfhydrylase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 421 amino acids
Theoretical weight: 46.14 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SK88 (Residues: 1-421; Coverage: 100%)
Gene names: TTHA0760, oah1
Sequence domains: Cys/Met metabolism PLP-dependent enzyme
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PLP 2 x PLP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE
Spacegroup: I41
Unit cell:
a: 149.095Å b: 149.095Å c: 219.299Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.187 0.217
Expression system: Escherichia coli

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