› 2cu1

Solution NMR

Solution structure of the PB1 domain of human protein kinase MEKK2b

Released:
DOI: 10.2210/pdb2cu1/pdb
PDB entry 2cu1 coloured by chain, ensemble of 20 models, front view.
PDB entry 2cu1 coloured by chain, ensemble of 20 models, side view.
PDB entry 2cu1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Inoue K, Nagashima T, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195161 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase kinase kinase 2 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.35 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9Y2U5 (Residues: 43-132; Coverage: 15%)
Gene names: MAP3K2, MAPKKK2, MEKK2
Sequence domains: PB1 domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links